Several decades after the events in the popular Blood: The Last Vampire anime film, amnesiac Saya Otonashi lives as a seemingly normal high-school student with her adoptive family in Okinawa. Horrible nightmares are the only hints at the violent life she once led, but her past is about to catch up with her and awaken the merciless warrior within. Asuka Katsura's manga series successfully expands upon the original Production I.G/Aniplex anime feature, delivering moments of jarring violence and thrilling action in a tale that spans several centuries.